MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded by mitochondrial DNA. It has attracted growing interest in research focused on metabolic health, cellular protection, and aging.
Studies have shown that MOTS-c activates AMPK pathways, improves glucose uptake, enhances insulin sensitivity, and promotes lipid oxidation. It may also play a role in mitochondrial function, inflammation control, and resistance to oxidative stress.
Key Research Areas:
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AMPK activation and metabolic regulation
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Insulin sensitivity and glucose metabolism
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Cellular resilience to oxidative stress
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Mitochondrial protection and longevity studies
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Anti-inflammatory and neuroprotective pathways
Note: For laboratory research use only. Not intended for human or veterinary applications.

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